Impact of recombinant DNA technology and molecular modeling on the practice of medicinal chemistry: Structure-activity analysis of opioid ligands
Mu-opioid receptors are found in human dental pulp.
"Studies in both animal and clinical models suggest that opioids exert their analgesic effects not only through activation of receptors in the CNS but also through interaction with peripheral opioid receptors. This study evaluated the presence and distribution of mu-opioid receptors in human dental pulp," researchers in the United States report.
"Human third molars indicated for extraction were removed, fixed in 4% paraformaldehyde and 0.2% picric acid.
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